At-Home Heart Failure Treatment Cuts Hospital Stays by Four Days

The multicenter trial, which enrolled 172 patients across 20 U.K. National Health Service hospitals, compared conventional intravenous diuretic therapy against an early discharge strategy using Lasix ONYU. Participants randomized to the at-home arm utilized a wearable abdominal pump to self-administer furosemide. Data showed this approach shortened index hospitalizations by an average of 5.5 days, providing patients with 4.0 more days alive and out of the hospital within the first month compared to those receiving standard inpatient care.

Pieter Muntendam, CEO of SQ Innovation, noted that the trial validates the safety of self-administering hospital-equivalent doses of furosemide. While patients in the at-home group received approximately 900 mg of the medication, clinical outcomes remained consistent with those observed in hospital settings. Serious adverse events occurred at comparable rates between both groups, with device-related complications reported in only 3% of cases. The findings suggest a viable path for shifting the burden of care for chronic heart failure edema away from resource-intensive hospital environments.